Celebrex vs. ibuprofen: Eseesega, mea e tutusa ai, ma o le fea e sili atu mo oe

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E iloa le gugu e mafua ai tiga ma tiga. E tele naua vailaʻau o loʻo i ai mo tiga o le gugu lea e mafai ona fenumiai o fea e inu. Lua vailaʻau masani i le NSAID (nonsteroidal anti-inflammatory drug) vaega o Celebrex (celecoxib) ma ibuprofen.

NSAIDs mafai ona lelei i le togafitia osteoarthritis ma rheumatoid gugu, faapea foi ma le tele o isi tulaga. E maua uma Celebrex ma ibuprofen i ituaiga lautele. E ui e avanoa le Celebrex i le talavai, e mafai ona e faʻatauina inumaga maualalo o le ibuprofen over-the-counter. Maualuga inumaga o ibuprofen e maua i talavai. Talu ai o Celebrex ma ibuprofen e i ai i le tutusa vasega o vailaʻau, latou e tutusa, ae o loʻo i ai foʻi ni mea iloga eseesega.

O a eseesega autu i le va o Lexapro vs. Zoloft?

Eseesega autu ile va ole Celebrex vs. ibuprofen
	Celebrex	Ibuprofen
Vasega fualaʻau	NSAID, COX-2 taofi	NSAID
Brand / tulaga lautele	Faʻailoga ma taʻatele	Rx: lautele OTC: ituaiga ma lautele
O le a le igoa lautele? O le a le igoa igoa?	Lautele: celecoxib	Faʻailoga: Motrin, Advil (OTC)
O a ituaiga (s) e sau ai le vailaʻau?	Capsules (50, 100, 200, 400 mg) Liquid form mo tamaiti o loʻo tuʻufaʻatasia e le fale talavai	Faʻamaonia-malosi laulau: 400 mg, 600 mg, 800 mg OTC: 200 mg papama / capsule / softgels, eseese chewables, suavai, ma mataua
O le a le fualaʻau masani?	Tagata matutua: 200 mg i aso uma ma meaʻai; maualuga 400 i le aso Suiga: 100 mg faʻalua faʻalua i aso uma Tamaiti lua tausaga ma sili atu: faʻamoemoe i le mamafa	Tagata matutua: 200 i le 800 mg tolu i le fa taimi i aso uma ma meaʻai; maualuga fualaʻau fesuiaʻi faʻalagolago i le tulaga Tamaiti: e fesuisuiaʻi faʻavae i tausaga, mamafa, ma le faʻavaeina
O le a le umi o le togafitiga masani?	Varies: vaiaso i tausaga	Varies: aso i vaiaso, o nisi tagata gasegase ave mo masina po o tausaga
O ai e masani ona faʻaaogaina vailaʻau?	Tamaiti lua tausaga pe sili atu; tagata matutua	Tamaiti ono masina ma luga atu; tagata matutua

Manaʻo le tau sili ile Celebrex?

Saini mo Celebrex tau faʻailo ma saili pe a suia le tau!

Maua tau mataala

Tulaga na togafitia e Celebrex ma Ibuprofen

Celebrex, o se vailaʻau e le faʻaaoga e teteʻe ai i le mafaufau (NSAID), o faailoa mo tulaga nei: osteoarthritis, rheumatoid gugu, gugu talavou rheumatoid i tagata gasegase lua tausaga ma sili atu, ankylosing spondylitis, matuitui tiga, autu dysmenorrhea, ma aiga adenomatous polyposis o se faʻaopoopo i masani tausiga.

Ibuprofen o se NSAID foi ma ua faʻailoa mai mo le faʻamamaina o faʻailoga ma faʻailoga o le osteoarthritis ma le rheumatoid galu, agamalu e feololo le tiga, ma muamua dismenorrhea.

Tulaga	Celebrex	Ibuprofen
Osteoarthritis	ioe	ioe
Rheumatoid gugu	ioe	ioe
Laʻitiiti juvenile rheumatoid (i tagata mamaʻi e lua tausaga pe sili atu)	ioe	Leai
Ankylosing spondylitis	ioe	Leai
Tiga matuitui	ioe	Leai
O le Peraimeri dismenorrhea	ioe	ioe
Aiga polyposis adenomatous faʻapitoa o se faʻaopoopo togafitiga	ioe	Leai
Agamalu e feololo le tiga	Leai	ioe

NSAID vailaʻau galue e ala i le polokaina prostaglandins (prostaglandins mafua ai tiga ma pupuga) mai le faia. Prostaglandin e faia e ni enzyme se lua, cyclooxygenase-1 (COX-1) ma le cyclooxygenase-2 (COX-2).

E sili atu le aoga o le Celebrex poʻo le Ibuprofen?

Celebrex e lauiloa o se filifilia COX-2 taofi. Aʻo avea pea ma NSAID pei o ibuprofen, o Celebrex e poloka COX-2, e ese mai i le ibuprofen, e poloka uma ai le COX-1 ma le COX-2. O le a le uiga o lea mea? O le COX-2 taofi e mafai ona faigofie i luga o le manava, ma le maualalo lamatiaga o le mafua ai papala puta.

I totonu suesuega togafitiga mo aoga, Celebrex faʻaalia:

• Faʻaitiitia le tiga soʻofaʻatasi i gasegase osteoarthritis
• Faʻaitiitia le tiga soʻoga ma fulafula i gasegase gugu rheumatoid
• Faʻaleleia atili i tagata mamaʻi ma tamaiti laiti rheumatoid gugu
• Faʻaleleia atili i tagata mamaʻi ma ankylosing spondylitis (i le tiga ogaoga, faʻamaʻi gaioiga, ma gaioiga faʻaletonu)
• Toomaga o feololo i tiga ogaoga mafua mai tiga taotoga po o dismenorrhea

I falemaʻi suʻesuʻega mo aoga, ibuprofen faʻaali :

• O se tali tutusa i aspirin i tagata mamaʻi ma osteoarthritis ma rheumatoid gugu mo tiga ma pupuga
• Toomaga o tiga mai episiotomy, nifo taotoga, ma dysmenorrhea

O le fea vailaʻau e sili atu ona aoga? E faigata ona taʻu atu. I le tasi suesue , Celebrex na faʻaalia e aoga tele pei o le ibuprofen mo tagata mamaʻi ma le osteoarthritis o le tulivae. O nisi suʻesuʻega faʻaalia ibuprofen ia sili atu le aoga, ae o isi faʻaiʻu Celebrex atonu e sili atu le aoga.

I le tulaga o le saogalemu, falemaʻi tofotofoga o Celebrex, faapea foi ma le filifilia NSAIDs (pei o ibuprofen) oʻo atu i le tolu tausaga ua faʻaalia ai le faateleina lamatiaga o matuia fatugao gaioiga, myocardial infarction, ma stroke, lea e mafai ona afaina. O le mea lea, o NSAID uma (e aofia uma ai Celebrex ma ibuprofen) ono ono fesoʻotaʻi ma lenei aʻafiaga. E le gata i lea, o NSAID uma, e aofia ai le Celebrex ma le ibuprofen, o loʻo i ai le faʻateleina o le ono aʻafia i faʻamaʻi GI, e pei o le toto ma papala

O le vailaʻau e sili ona lelei mo oe e faʻatoa mafai ona fuafuaina e lau fomaʻi, o ia e mafai ona amanaʻia le ata atoa o ou tulaga faʻafomaʻi, mea e ono aʻafia ai, talaʻaga o le soifua maloloina, ma isi vailaʻau o loʻo e inuina.

Manaʻo le tau sili ile Ibuprofen?

Saini mo Ibuprofen tau faʻailo ma saili pe a suia le tau!

Maua tau mataala

Faʻatupeina ma faʻatusatusaina tau o Celebrex vs. Ibuprofen

E masani ona ufiufi le Celebrex e le inisiua ma Medicare Vaega D i lona tulaga lautele o le celecoxib. O se talavai masani o le a mo 30 capsules o 200 mg celecoxib. O le tau i fafo o le taga e tusa ma le $ 217.49 ae e mafai ona e maua le celecoxib mo le $ 105-145 i faleoloa o loʻo auai ma le coupon a le SingleCare.

Ibuprofen e masani ona ufiufi e le inisiua ma Medicare Vaega D, i malosiʻaga faʻatonuina o 400 mg, 600 mg, ma le 800 mg. E eseʻese talavai a le fomaʻi. Mo se faʻataʻitaʻiga, o le tau faʻatau atu mo le 30 papa o le 800 mg ibuprofen tau mai soʻo se mea mai le $ 6-30. Faatasi ai ma le coupon SingleCare, o le tau mo ibuprofen e $ 4-8.

	Celebrex	Ibuprofen
Masani ufiufi e inisiua?	Ioe; lautele	Ioe; malosi talavai
Masani ufiufi e Medicare Vaega D?	Ioe; lautele	Ioe; malosi talavai
Tulaga masani	30, 200 mg capsules o generic celecoxib	30, 800 mg laupapa o ibuprofen
Masani Medicare Vaega D copay	$ 0-150	$ 0-14
Tau nofofua	$ 105-145	$ 4-8

Aafiaga o le Celebrex vs. Ibuprofen

O mea e masani ona tupu i le Celebrex ma le ibuprofen e aofia ai le tiga o le manava, manava tatā, le manava, ma le tiga o le ulu. Vaʻai le vaega o lapataiga mo nisi faʻamatalaga e uiga i le faʻamaʻi o le fatu ma le afaina o le toto GI.

	Celebrex	Ibuprofen
Aafiaga Itu	E talafeagai?	Faafia	E talafeagai?	Faafia *
Tiga o le manava	ioe	4.1%	ioe	3-9%
Manava tata	ioe	5.6%	ioe	3-9%
Dyspepsia (manava)	ioe	8.8%	ioe	3-9%
Tigā ulu	ioe	15.8%	ioe	3-9%

* O le tele o aʻafiaga o le ibuprofen e le o tuʻuina mai ma faʻamatalaga vailaʻau; naʻo na aafiaga na tupu ile 3-9% o tagata mamaʻi.

Punavai: DailyMed (Celebrex) , Aso Taʻitasi ( ibuprofen )

E leʻo se lisi atoa; isi aafiaga itu ono tupu. Talanoa ma lau fomaʻi faʻapitoa mo auiliiliga.

Fetuʻunaʻiga o vailaʻau o Celebrex ma Ibuprofen

Celebrex ma ibuprofen e tele a tutusa fesoʻotaʻiga ma isi talavai fualaʻau. O vailaʻau uma e lua e faʻafesoʻotaʻi ma le toto manifinifi e pei o Coumadin (warfarin), vailaʻau toto faʻatosina (ACE inhibitors, ARBs, ma beta blockers), antidepressants, ma diuretics pei o hydrochlorothiazide ma methotrexate. Faʻatalanoa lau fomaʻi tausi soifua mo le taʻitaʻi

E tatau ona 'alofia le' ava malosi peʻa inu Celebrex poʻo le ibuprofen. Faʻaaogaina se tasi o nei vailaʻau ma le ava malosi mafai faʻateleina ai le ono maua o le GI (manava) tafetoto po o le fulafula. O le tuʻufaʻatasia e ono mafua ai le faʻaleagaina o fatugaʻo poʻo fatuga faʻaletonu.

Lenei o se vaega faʻavasega o fualaʻau feutanaʻi. Faʻafesoʻotaʻi lau fomaʻi soifua maloloina mo nisi faʻamatalaga.

Fualaau faasaina	Vasega o Fualaʻau	Celebrex	Ibuprofen
Coumadin (warfarin)	Anticoagulant	ioe	ioe
Zestril (lisinopril), Cozaar (losartan), ma isi	ACE taofi, ARBs	ioe	ioe
Tenormin (atenolol), Toprol XL poʻo le Lopressor (metoprolol)	Beta poloka	ioe	ioe
Diflucan (fluconazole)	Antifungal	ioe	Leai
Lasix (furosemide), hydrochlorothiazide	Diuretics	ioe	ioe
Naproxen, Mobic (meloxicam)	Isi NSAIDs	ioe	ioe
Methotrexate	Antimetabolite	ioe	ioe
Zoloft (sertraline), Paxil (paroxetine), Prozac (fluoxetine), Effexor (venlafaxine), Desyrel (trazodone), Elavil (amitriptyline), ma isi	Antidepressants	ioe	ioe
Ava Malosi	Ava Malosi	ioe	ioe

Lapataiga a Celebrex ma Ibuprofen

E tatau ona 'alofia le Celebrex i tagata mamaʻi o loʻo afaina i le NSAID, faʻapena foʻi ma tagata mamaʻi e afaina i le sulfa. Ibuprofen tatau ona aloese mai tagata mamaʻi o loʻo afaina i le NSAIDs.

Talu ai o vailaʻau uma e lua o NSAIDs, Celebrex ma ibuprofen e tutusa lava lapataiga. E i ai la latou lapataiga i le atigipusa (o le lapataʻiga sili ona malosi e pei ona manaʻomia e le Food and Drug Administration, poo le FDA). Celebrex po ibuprofen ono faʻateleina le ono aʻafia o matuia gaioiga gaioiga, MI (myocardial infarction, po o le fatu faʻamaʻi), ma stroke, uma na mafai ona afaina. O NSAID uma e i ai se tulaga tali tutusa, lea e faʻateleina ai le umi e te faʻaaogaina ai. Tagata mamaʻi ma faʻamaʻi fatu pe o loʻo maua i le faʻamaʻi o le fatu fatu e sili atu ona lamatia. E le tatau ona faʻaaogaina le Celebrex poʻo le ibuprofen mo le tiga i le taimi o le taotoga o le alatoto (CABG).

Faʻapea foi ma le lapataiga pusa o le ono aʻafia o le ogaoga GI, poʻo gastrointestinal mea na tutupu, e aofia ai le toto, papala, ma perforation o le manava poʻo gaʻau, lea e mafai ona afaina. Soʻo se tasi o nei gaioiga mafai ona tupu i soo se taimi, ma aunoa ma le lapataʻi faʻailoga. O tagata mamaʻi ma i latou e iai le talaʻaga o papala pe faʻapipiia le toto i le toto e sili atu le avanoa mo faʻalavelave ogaoga o le GI.

O isi lapataʻiga a Celebrex ma ibuprofen e aofia ai:

• Tulaga lamatia o le maualuga o le ate enzymes ma, seasea, ogaoga hepatic tali atu.
• Tulaga fou pe faʻateteleina le toto maualuga (toto maualuga). Faʻaaoga ma le faʻaeteete i gasegase toto maualuga; vaʻai totoʻa le toto i le taimi o togafitiga.
• Faatumauina o le suavai ma le edema. Faʻaaoga ma le faʻaeteete i tagata mamaʻi o loʻo taofia le vai poʻo le fatu faʻaletonu
• Fatugao papillary nekrosis / isi manuʻa manuʻa ma umi faʻaaoga. Faʻaaoga ma le faʻaeteete i tagata matutua, tagata mamaʻi e faʻaleagaina le fatugao o le fatuga, fatu fatu, le aoga le afaina, ma tagata mamaʻi e ave diuretics, ACE inhibitors, poʻo le angiotensin II poloka.
• Tali a Anaphylactoid. Aua le faʻaogaina mo tagata mamaʻi Samter's tafatolu .
• Ogaoga tali paʻu e mafai ona tupu e pei o exfoliative dermatitis, Stevens-Johnson syndrome (SJS), ma le oona epidermal nekrolysis (TEN), lea e mafai ona afaina ma tupu e aunoa ma se lapataiga. Faʻamutaina Celebrex ma saili vave togafitiga faʻafomaʻi pe a fai o le mageso po o le paʻu tali atu tupu.

E faʻatapulaʻa faʻamatalaga ile faʻaaogaina ole NSAID ile maʻitaga. O le faʻaaogaina o NSAID uma, e aofia uma ai Celebrex ma ibuprofen, i le taimi o le tolu masina o le maʻitaga, faʻateleina le ono aʻafia o vave tapunia o le fetal ductus arteriosus . O le mea lea, e le tatau ona faʻaaogaina NSAIDs pe a maeʻa le 30 vaiaso o faʻailoga.

Faʻatalanoa lau fomaʻi faʻapitoa e uiga ia Celebrex poʻo ibuprofen faʻaaoga i maʻito. A faʻapea o loʻo e inuina le Celebrex poʻo le ibuprofen ma iloa ua e maʻitaga, faʻafesoʻotaʻi lau auaunaga faʻafomaʻi mo se faʻatonuga.

E faʻatapulaʻa faʻamaumauga on Celebrex ma ibuprofen ma faʻasusu susu; faʻafesoʻotaʻi lau fomaʻi mo le taʻitaʻiga.

Fesili masani e uiga ia Celebrex vs. Ibuprofen

O le a le Celebrex?

Celebrex o se nonsteroidal anti-inflammatory drug (NSAID) faʻailoa mai mo tulaga nei: osteoarthritis, rheumatoid gugu, juvenile rheumatoid galu i tagata gasegase lua tausaga ma luga atu, ankylosing spondylitis, matuitui tiga, autu dysmenorrhea, ma aiga adenomatous polyposis o se faʻaopoopo i masani popole

O le a le Ibuprofen?

Ibuprofen o se NSAID ma faʻaaogaina e togafitia ai faʻailoga ma faʻailoga o le osteoarthritis, rheumatoid gugu, agamalu e feololo tiga, ma muamua dismenorrhea.

E tutusa Celebrex ma Ibuprofen?

Talu ai o vailaʻau uma e lua o NSAIDs, e tutusa ma e tutusa a latou aʻafiaga ma lapataʻiga. E eseese i faʻailoga ma tau. Vaʻai luga atu e saili atili e uiga i mea tutusa ma eseesega.

E sili atu le Celebrex poʻo le Ibuprofen?

O vailaʻau uma e lua e mafai ona aoga tele i le togafitia o le gugu ma isi tulaga. Faʻamoemoeina i tulaga (s) o loʻo e togafitia, ma le amanaʻia o isi faʻafomaʻi ma tulaga lamatia oe, faʻapea foi ma isi vailaʻau o loʻo e aveina, lau fomaʻi mafai ona fesoasoani faʻutuaina talafeagai vailaʻau mo oe.

Mafai ona ou faʻaaogaina Celebrex poʻo Ibuprofen aʻo ou maʻito?

A e faʻapea ua e maʻi ma ua e faʻaaogaina le Celebrex poʻo le ibuprofen faʻafesoʻotaʻi lau fomaʻi soifua maloloina mo fautuaga.

E le tatau i fafine maʻitaga ona faʻaaogaina nei NSAID pe a maeʻa le 30 vaiaso o le maʻitaga. Faʻaaogaina Celebrex ma ibuprofen i le taimi o le tolu masina tolu o maitaga mafai faʻateleina le ono aʻafia o vave vave tapunia o le fetal ductus arteriosus.

Mafai ona ou faʻaaogaina Celebrex poʻo Ibuprofen ma le ava malosi?

Leai . Faʻaaogaina se tasi o nei vailaʻau ma le ava malosi mafai faʻateleina ai le ono maua o le GI (manava) tafetoto pe manava fulafula. O le tuʻufaʻatasia e ono mafua ai le faʻaleagaina o fatugaʻo poʻo fatuga faʻaletonu.

E sili atu le aoga o le Celebrex nai lo le ibuprofen?

O vailaʻau uma e lua e mafai ona aoga tele i le togafitia o le tiga o le gugu ma isi tulaga. Talanoa ma lau fomaʻi tausi soifua e aʻoaʻo ai vailaʻau e sili ona lelei mo oe na tuʻuina atu ou maʻi, sitaili o le soifua maloloina, ma isi vailaʻau e te ono inuina.

Aisea na latou ave ai Celebrex mai le maketi?

O loʻo iai pea Celebrex ile maketi e oʻo mai nei. Vioxx (rofecoxib), o se vailaʻau tali tutusa ma Celebrex, sa aveʻese mai le maketi e lona gaosi oloa, Merck, i le 2004, ona o le faʻateleina o le aʻafiaga o le fatu gaioiga ma le faʻaaogaina pea. I le 2005, o le isi vailaʻau faʻapena, Bextra (valdecoxib), sa toso ese le maketi e le gaosi oloa Pfizer mo tutusa mafuaʻaga.

O Celebrex o se tiga?

Celebrex o se NSAID (nonsteroidal anti-inflammatory) fualaʻau e fesoasoani i faʻailoga o le tiga ma le fulafula mai tulaga eseese (vaʻai luga). Talu ai e naʻo COX-2 enzymes e aoga, atonu e sili atu le sefe mo le manava, e ui lava o loʻo iai pea se faʻamaʻi GI.