O a NSAIDs?

Faʻamatalaga o vailaʻau

Lisi NSAID | O a NSAIDs? | Faʻafefea ona latou galue | Faʻaaogaina | O ai e mafai ona ave NSAIDs? | Saogalēmū | Aʻafiaga itu | Tau

Afai na e masani i soʻo se ituaiga o tiga poʻo le fulafula, o le avanoa ua e inuina se vailaʻau NSAID mo se taimi puʻupuʻu mapusaga (analgesic aafiaga). NSAIDs o nonsteroidal vailaʻau e teteʻe ai i le mafaufau. Faʻaaogaina i tamaiti ma tagata matutua, latou te fesoasoani i le tele o maʻi eseʻese e ono mafua ai tiga poʻo le fulafula. Faitau pea e aʻoaʻo mea uma e uiga i le NSAIDs-e aofia ai igoa masani o igoa, faʻaaogaina, ma le saogalemu faʻamatalaga. Lenei siata lisiina le sili ona taatele NSAIDs ma tau faʻamatalaga.

Lisi o NSAIDs
Igoa igoa (igoa lautele)	Tau averesi tinoitupe o mea lautele	Tau nofofua	Aoao atili
Advil, Motrin (ibuprofen) *	$ 50 i le 30, 800 mg laupapa	Maua ni ibuprofen coupons	Ibuprofen auiliiliga
Aleve, Anaprox, Anaprox DS, Naprosyn, Naprelan (naproxen) *	$ 53 i le 30, 500 mg laupapa	Maua ni coupon naproxen	Auiliiliga Naproxen
Celebrex (celecoxib)	$ 360 mo le 30, 200 mg capsules	Maua le coupon Celebrex	Celebrex auiliiliga
Clinoril (sulindac)	$ 65 mo le 60, 200 mg laupapa	Maua le couponil coupon	Clinoril auiliiliga
Feldene (piroxicam)	$ 183 mo le 30, 10 mg capsule	Maua le coupon Feldene	Faamatalaga auiliili
Indocin (indomethacin)	$ 32 mo le 30, 50 mg capsule	Maua le Indocin coupon	Indocin auiliiliga
Lodine (etodolac)	$ 70 mo le 60, 400 mg laupapa	Maua sau coupine coupine	Auiliiliga a le Lodine
Mobic (meloxicam)	$ 210 mo le 30, 15 mg papamaa	Maua ia Mobic coupon	Mobic auiliiliga
Orudis (ketoprofen)	$ 52 mo le 30, 75 mg laupapa	Maua le coupon Orudis	Orudis auiliiliga
Relafen (nabumetone)	$ 80 mo le 60, 500 mg laupapa	Maua le Relafen coupon	Faʻamatalaga auiliili
Toradol (ketorolac)	$ 127 mo le 20, 10 mg papamaa	Maua le coupon Toradol	Toradol auiliiliga
Voltaren, Voltaren-XR (diclofenac sodium, tautala)	$ 25 mo le 30, 50 mg laupapa	Maua le Voltaren (oral) coupon	Voltaren (oral) auiliiliga
Gel Voltaren (diclofenac, autu) *	$ 82 mo le faagaau 100-kalama	Maua Voltaren (autu) coupon	Voltaren (autu) auiliiliga

* Avanoa i talavai ma faʻavae OTC

Isi NSAID aofia ai:

• Ansaid (flurbiprofen)
• Arthrotec (diclofenac / misoprostol)
• Cataflam (diclofenac potassium)
• Daypro (oxaprozin)
• Disalcid (salsalate)
• Dolobid (diflunisal)
• Flector (diclofenac autu)
• Meclomen (meclofenamate)
• Nalfon (fenoprofen)
• Pennsaid (diclofenac autu)
• Ponstel (mefenamic acid)
• Solaraze (diclofenac autu)
• Tolectin (tolmetin)
• Zipsor (diclofenac potassium)

O a NSAIDs?

O vailaʻau e le faʻaaoga e puipuia ai le mafaufau, o vailaʻau lauiloa e togafitia ai le tiga ma le fulafula mai tuʻaiga eseese e pei ole gugu, tiga o le tua, ma le ulu tiga. E mafai foʻi ona latou fesoasoani e faʻaititia le fiva. E ui lava e tele NSAID talavai, o isi e avanoa i luga o le faleoloa (OTC) pei ole aspirin ma ibuprofen.

Manatua o Tylenol, o loʻo iai le acetaminophen, e masani ona taʻua ma nei vailaʻau, ae Tylenol e le o se NSAID.

Faʻafefea ona galue NSAIDs?

E galue le NSAID ile poloka o enzymes e taʻua ole COX-1 ma le COX-2. COX tu mo le cyclooxygenase. O nei enzymes faia prostaglandins, lea mafua ai tiga ma pupuga. I le poloka o nei enzymes, o lou tino e maua ai ni nai prostaglandins, mafua ai laititi tiga ma pupuga. ( Celebrex o le NSAID o le COX-2 taofi. I le poloka naʻo le COX-2, e ono laʻititi ni aʻafiaga leaga i le manava.)

NSAIDs e aoga ma e masani ona faʻatonutonu le tiga, faʻasaoina tagata mamaʻi mai le inuina o ni vailaʻau malosi e pei ole opioids, ia e tele atu aafiaga ogaoga ma ono maualuga ai le faʻataʻitaʻi ma le faʻamoemoeina.

A i ai ia te oe agamalu i feololo tiga poʻo le fulafula e manaʻomia ai se NSAID, isi auala e ono fesoasoani foi. Fesili i lau fomaʻi soifua maloloina mo taʻitaʻi faʻafomaʻi i luga o isi togafiti togafiti tiga e pei o le aisa poʻo le vevela, togafitiga faʻamalositino, ma malologa.

O a mea e faʻaaoga ai NSAIDs?

NSAIDs e aoga mo le tele o tuutuuga e mafua ai le agamalu e feololo le tiga ma le fulafula, pei o:

• Tulimanu o le tua
• Ua tiga maso
• Taʻaloga manuʻaga / sprains
• Ulu ulu
• Fiva
• Tiga nifo
• Rheumatoid gugu
• Galu o le rheumatoid talavou
• Osteoarthritis
• Tendonitis
• Ankylosing spondylitis
• Tofo o falaoa
• Bursitis
• Maʻi masina i taimi paʻu

A o eseʻese faʻailoga e vaʻaia i oloa, fesili i lau fomaʻi faʻapitoa mo fautuaga faʻafomaʻi poʻo le a le mea e faʻamama ai le tiga e sili ona lelei mo lou tulaga.

O ai e mafai ona ave NSAIDs?

Ae

Tele aliʻi matutua e mafai ona ave NSAIDs seʻi vagana ua latou paʻuʻu i lalo o soʻo se vaega faʻatapulaʻaina i lalo.

Fafine

Tele fafine matutua e mafai ona ave NSAIDs seʻi vagana ua latou paʻuʻu i se vaega faʻatapulaʻa lisi atu i lalo. E le tatau i fafine maʻitaga ona ave NSAID ile tolu masina tolu o le maʻitaga ona e ono afaina ai se pepe e leʻi fanau mai.

Tamaiti

NSAID e leʻo faʻamatalaina, pei ole Advil ma Motrin, e avanoa mo tamaiti e matutua atu ile 6 masina, ae ia e mautinoa e siaki le fualaʻau talafeagai ma lau fomaʻi tamaiti poʻo le fomaʻi. E eseese fesuiaiga i le fausiaina, tausaga, ma le mamafa. Nisi faʻatulagaina e sili atu faʻalauteleina, o lona uiga o le tamaititi o le a maua sili vailaʻau i se laʻititi aofaʻi. O le mafuaaga lena e taua ai tele le faitau i le Faʻailoga o mea moni o vailaʻau mo le oloa faʻapitoa, ma siaki siaki lua faʻafomaʻi pe a e le mautinoa. Faʻapea foi, faʻaaoga se ipu inu vai poʻo se tui e fua ai le fualaʻau talafeagai. Aua le faʻaaogaina sipuni e fua ai sipuni, aua e mafai ona le saʻo mo le fuaina o vailaʻau.

E ui e avanoa Aleve OTC, ae le tatau ona faʻaaogaina i tamaiti e laiti ifo i le 12 tausaga le matutua.

Fuainumera NSAIDs eseese i tuutuuga o tausaga ma faʻailoga, o lea fesili i lau fomaʻi tausi soifua pe a iai sau fesili.

Matua

NSAIDs o loʻo i luga o le Lisi o pia o vailaʻau e ono le talafeagai mo matutua matutua. E maualuga le aʻafiaga o le manava toto poʻo papala i tagata ua matutua nai lo le 75 tausaga. Aveina o le proton pump inhibitor pei o le Prilosec e mafai ai ona tuʻu i lalo le aʻafiaga o le manava, ae le faʻateʻaina le aʻafiaga. E tatau foi i tagata matutua ona aloese mai le NSAIDs ona o le faateleina o le lamatiaga mo le fatu fatu, taofia vai, ma fatugai faʻaleagaina.

O saogalemu NSAIDs?

Tapulaa ole NSAID

Aua le avea le NSAID peʻa e:

• E afaina i nisi NSAIDs.
• Maua se talaʻaga o le maʻemaʻe poʻo le tali atu i faʻamaʻi mai le aspirin poʻo isi NSAIDs.
• O le a toeititi faia (pe na faʻatoa maua) CABG taotoga.
• O loʻo i le lona tolu kuata o le maʻito. A faʻapea o loʻo e i le muamua poʻo le lona lua trimester, pe afai oe faʻasusu, fa' fesili i lau fomaʻi faʻapitoa mo fautuaga faʻafomaʻi.

Lapataʻiga a le NSAID

Uma NSAIDs i ai a lapataiga pusa uliuli . O se lapataiga uliuli o se lapataʻiga sili ona matuia e pei ona manaʻomia e le FDA (United States Food and Drug Administration). O lenei lapataiga e aofia ai:

• Tulaga lamatia ole fatu : NSAIDs mafua ai le faʻateleina lamatiaga o le toto pala, fatu fatu, ma stroke, lea e mafai ona afaina. O le lamatiaga o loʻo iai i le amataga o togafitiga, ma o le aʻafiaga e faʻateleina ai le umi o le faʻaogaina o le vailaʻau. NSAIDs le tatau ona faʻaaogaina muamua pe ina ua maeʻa coronary artery bypass graft (CABG) taotoga.
• Gastrointestinal (GI) tulaga lamatia : NSAIDs faʻateleina le ono o le toto, afaina o le manava ufiufi / papala, ma perforation o le manava ma gaʻo. Lenei mafai ona afaina. Nei GI faʻafitauli e mafai ona tupu i soʻo se taimi i le NSAID faʻaaogaina ma aunoa ma se lapataiga. O mea e ono aʻafia ai e aofia ai tagata matutua ma tagata mamaʻi ma le gasegase o le GI ma / poʻo papala.

O isi lapataʻiga e aofia ai:

• I ni tulaga seasea lava, e mafai ona tupu faʻafitauli i le ate. E mafai ona matuia pe afaina ai foi. Faʻailoa i lau fomaʻi pe a iai ni au faʻailoga e pei o le niniva, lelava, mageso, paʻu lalo o le manava, jaundice, poʻo le manava tata.
• Toto toto tatau ona mataʻituina i le taimi o togafitiga.
• Talu ai o NSAIDs faʻateleina le aʻafiaga o le fatu faʻaletonu ma edema, e tatau ona masani ona 'alofia i tagata e ogaoga fatu fatu.
• Faʻaaoga mo se taimi umi e mafai ona mafua ai faʻafitauli i fatugaʻo ma e tatau ona masani ona alofia i tagata mamaʻi ua maua i faʻamaʻi ogaoga le fatu.
• Saili se fesoasoani faʻafomaʻi pe a fai o faʻailoga o se faʻalavelave e tupu i le anaphylactic, e pei o le mageso, faigata ona manava, poʻo le fulafula o laugutu, foliga, poʻo le laulaufaiva.
• NSAIDs mafai ona mafua ai ogaoga paʻu tali atu e pei o Stevens-Johnson Syndrome po o le oʻona epidermal nekrolysis (TEN). Nei mafai ona afaina ma tupu e aunoa ma se lapataiga. Taofi le ave o le NSAID ma maua se fesoasoani faʻafuaseʻi pe a fai e te maua se paʻu i le tino. Aua le avea NSAIDs pe a fai na iai sau paʻu muamua i le NSAID.
• NSAIDs mafai mafua mafua anemia. O le aʻafiaga o le toto mai NSAID e faʻateleina ma le faʻaaogaina o nisi vailaʻau pei o le corticosteroids, anticoagulants (pei o warfarin), antiplatelets, poʻo SSRI poʻo SNRI antidepressants.
• Afai e te umi se NSAID, fesili i lau fomaʻi e uiga i suʻega o lab. Ona o tulaga lamatia uma e fesoʻotaʻi ma NSAIDs, e sili ai le ave o le inumaga maualalo mafai, mo le puʻupuʻu taimi. Afai o loʻo e faʻaaogaina le OTC NSAID, fesili i lau fomaʻi ae e te leʻi faʻaaogaina mo le sili atu i le 10 aso. Paʻu tiga atonu e manaomia ai se isi vailaʻau.

Taʻu i lau fomaʻi soifua maloloina e uiga i vailaʻau uma e te inuina, aofia ai ma talavai, OTC, ma vitamini, ina ia mafai ona ia mautinoa o le NSAID o loʻo saogalemu ma isi vailaʻau e te inu. E fesoʻotaʻi NSAID ma ni vailaʻau pei o SSRI poʻo SNRI antidepressants, anticoagulants, lithium, ACE inhibitors, ARBs, ma diuretics.

E le tatau ona faʻaaogaina NSAID ile tolu masina tolu o le maitaga, aua e mafai ona afaina ai se pepe e leʻi fanau mai.

Manatua NSAID

• Ketorolac injection injection manatuaina (Mati 2020)
• Ketorolac injection injection manatuaina (Aperila 2019)
• Ibuprofen tautala tuʻufaʻatasi (Ianuari 2019)
• Tamaiti 'ibuprofen manatuaina (Tesema 2018)

O Vioxx ma Bextra na avea uma ma COX-2 taofi na aveʻese mai le maketi ona o faʻafitauli ogaoga i le fatu.

Mafai ona e ave NSAIDs aʻo maʻito po o susu?

Aua le avea NSAIDs i le tolu masina tolu o maʻito. O vailaʻau nei e mafai ona afaina ai se pepe e leʻi fanau mai. Afai o loʻo e i le muamua poʻo le lona lua trimester, pe afai oe ua uma ona ave se NSAID ma iloa ai o oe o maʻito, faʻafesoʻotai lau auaunaga faʻafomaʻi mo taiala.

Afai o loʻo e susu, faʻafesoʻotai lau polofesa mo se fautuaga faʻafomaʻi.

O NSAIDs faʻatonutonu vailaʻau?

Leai, ole NSAID e leʻo pulea ni vailaʻau.

O aʻafiaga masani ole NSAIDs

NSAID tiga e faʻamamaina tiga e masani ona onosaʻia lelei ae mafai ona mafua ai le tele o aʻafiaga itu, nisi o na e mafai ona ogaoga. O aʻafiaga e masani ona aʻafia e aofia ai le tiga o le manava o le GI (gastrointestinal) e pei o tiga o le manava, manava manava, manava tata, kesi, fatu o le fatu, niniva, ma puaʻi. O le niniva o se masani masani aʻafiaga.

Isi, ogaoga aafiaga itu mafai ona tupu. E mafai ona aofia ai:

• O faʻafitauli o le fatu e pei o le fatu fatu, papala, toto maualuga (toto maualuga), poʻo le fatu faʻaletonu
• Fatugao poʻo faʻafitauli o le ate
• O faʻafitauli o le GI e pei o le tafetoto ma papala i le manava ma le tina
• Maualalo toto mumu
• Paʻu e lamatia ai le ola poʻo le tali atu i faʻalavelave
• Osofaʻi osofaʻi i tagata maʻi sela

A iai ni faʻailoga ia te oe, ia faʻataʻitaʻi togafitiga faʻafuaseʻi.

• Faigata manava poʻo le manava puʻupuʻu
• Tiga o le fatafata
• Vaivaiga i le tasi itu o le tino
• Tautalaga lemu
• Fula o foliga poʻo le faʻaʻi

Taofi le ave o lau NSAID ma vili vave lau fomaʻi pe a fai e iai se tasi o faʻailoga nei:

• Faanoi
• Lagona le lelava tele pe vaivai
• Paʻu, mageso le paʻu, pe paʻu foi ile fiva
• Lanu samasama o le paʻu pe paʻepaʻe o mata
• Flulike auga
• Faʻalu toto
• Lanu uli, faʻatuai, poʻo faʻatotoga toto
• Fula o lima / vae / lima / vae

E leʻo se lisi atoa o aʻafiaga. Faʻatalanoa lau fomaʻi tausi soifua mo le atoa lisi o aʻafiaga.

E fia le tau ole NSAID?

NSAIDs o se filifiliga lauiloa i le au tausi soifua maloloina ona latou e le gata lelei ae taugofie faʻapea foi. E mafai ona e faʻatau OTC NSAID mo le $ 5 ma luga atu, faʻamoemoe i le afifi tele ma le faʻatulagaina. Talosaga-malosi NSAIDs e faʻatauoloa foʻi, ma tau e eseese e oloa, malosi, ma aofaʻi. E mafai ona e faʻaoga se avanoa Nofofua card e sefe ai tupe i lau pepa talavai NSAID ma e oʻo lava i pepa OTC ma se faʻamaoniga lelei.